Product Overview

It is usually a colorless or light yellow transparent liquid with a strong pungent odor. Its melting point is about -17 ° C, boiling point is between 88-97 ° C, density is about 1.07 g/cm ³ (20 ° C), and flash point is 18-21 ° C (closed cup), indicating its high flammability. This substance is soluble in solvents such as water and alcohols, but may undergo hydrolysis when in contact with water. The vapor density (air=1) is 2.62, the self ignition temperature is 427 ° C, and the lower explosive limit is 1.1% (volume fraction). ‌
‌Product Features

Thioacetic acid is an organic synthetic reagent commonly used in acylation reactions and Michael addition reactions, such as converting alcohols to acetic acid thiol esters or participating in conjugate addition as a nucleophile.

Scope of application

1. Pharmaceutical synthesis: As a thiolating agent, it is used for the synthesis of thioctic acid, Captopril (antihypertensive drug), and cephalosporin antibiotics. It can also be used for the synthesis of compounds such as cysteine and mercaptocarboxylic acid. It is also a raw material for the synthesis of hormone modifiers and detoxifiers.

2. Chemical and scientific research: Can be used as an acetylthio agent to participate in the synthesis of high-value fine chemicals such as thiols and thioethers; Can be used for detecting cobalt and lead, determining molybdenum, and can replace hydrogen sulfide as a metal precipitant in dilute ammonia solution; It is also a substrate for acetylcholinesterase in tissue chemistry and can be used for the synthesis of aldehydes and ketones.

3. Daily chemicals and others: As an intermediate of essence and spice, it can improve the stability of daily chemicals; It can participate in enantioselective addition reactions in organic reactions and is used for the synthesis of antifungal drugs such as fluconazole.